PHARMACOLOGICAL POTENTIAL, MEDICINAL USES, AND BIOACTIVE PROPERTIES OF AZADIRACHTA INDICA (NEEM): A SYSTEMATIC REVIEW

Title

PHARMACOLOGICAL POTENTIAL, MEDICINAL USES, AND BIOACTIVE PROPERTIES OF AZADIRACHTA INDICA (NEEM): A SYSTEMATIC REVIEW

Author

1. MUSKAN SHRESTHA, Student, KALINGA UNIVERSITY, India
2. DEVESH KASHYAP, Student, KALINGA UNIVERSITY, India
3. Dr. Shilpi Shrivastava, Professor, KALINGA UNIVERSITY, India

Abstract

Scientific name of neem is AZADIRACHTA INDICA. ARISHTHA is the sanskrit name of neem tree that means helper for sickness. Neem also has various medicinal property and has been used in worldwide in recent years. It is also used in ayurveda medicine, homoeopathic and Unani medicine and also become the centre of attention of in modern medicine. It also elaborates a wide variety of biologically active compound that are chemically different and structurally elaborated. In neem tree all parts like leaves, flower, fruits, seeds, root and bark are used for the treatment of skin diseases, infection, dental disorder, inflammation, etc.

 Neem leaf extract is also known as IRAB has been used against malaria, HIV- AIDS and cancer. Its element has been indicated to exhibit anti-inflammatory, anti-hyperglycaemic, antioxidant, antidiabetic immune modulatory, antiviral, antimutagenic and anticarcinogenic properties. Neem also consists of compounds like flavonoids, glycosides, tannins and aliphatic compounds. It also useful for heart illnesses, hepatitis, psoriasis, ulcers, etc.

Neem are used in various research fields of food safety, virology, mycology, bacteriology, etc. The biological, pharmacological and toxicological properties of neem can be analyses by modern techniques like NMR spectroscopy, infra-red spectroscopy, HPLC-MS, etc. 

Keywords

Conclusion

Neem is one of the greatest harmless biological sources for creating modern medications. As result a wide range of neem extracts have advantages that go beyond traditional medicinal folklore. We can now use neem extract as modern medical adjuvants on humans, animals and plants by knowing there of scientific and technical advancements. The significance of “kalpavirksha” is potential for both therapeutic and economic use in support of sustainable development can be investigated.

The therapeutic uses make it an essential part of ayurvedic, Unani and homeopathic medicine. Each system employs neem in a different way, they all acknowledge and its benefits as natural immune-stimulating, detoxifying, anti-inflammatory and antiseptic. In traditional healing systems, it is highly valued for its capacity to treat a wide range of illnesses. Neem continues to be a vital component of holistic and natural medicine and contemporary studies support this ancient use. With wide range of biological activities, neem is powerful medicinal plant that are0 used to prevent and treat a wide range of illnesses. It is promising optional for both conventional and contemporary therapeutic applications due to its multi-targeted actions and natural nature.

Author Contrubution

Author A conceptualized and designed the study. Author A and Author B performed the literature search, data analysis, and manuscript drafting. Both authors critically revised the manuscript and approved the final version.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Conflict of Interest

The authors declare that there is no conflict of interest regarding the publication of this article.

Data Sharing Statement

All data generated or analyzed during this study are included in this published article.

Software And Tools Use

Acknowledgements

The author would like to acknowledge all researchers and authors whose work has been cited in this systematic review.