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<article xlink="http://www.w3.org/1999/xlink" mml="http://www.w3.org/1998/Math/MathML" xsi="http://www.w3.org/2001/XMLSchema-instance" ali="http://www.niso.org/schemas/ali/1.0/" noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" article-type="research-article" dtd-version="1.1" lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">isrdo-SRJMH</journal-id><journal-id journal-id-type="pmc">isrdo-SRJMH</journal-id><journal-id journal-id-type="nlm-ta">isrdo-SRJMH</journal-id><journal-title-group><journal-title>Scientific Research Journal of Medical and Health Science</journal-title><abbrev-journal-title abbrev-type="publisher" pub-type="epub">SRJMH</abbrev-journal-title></journal-title-group><issn>2584-1521</issn><publisher><publisher-name>ISRDO</publisher-name><publisher-loc>Gujarat,India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">M-10436</article-id><article-id pub-id-type="doi"/><article-categories><subj-group subj-group-type="categories"><subject>Pharmacology</subject></subj-group></article-categories><title-group><article-title>PHARMACOLOGICAL POTENTIAL, MEDICINAL USES, AND BIOACTIVE PROPERTIES OF AZADIRACHTA INDICA (NEEM): A SYSTEMATIC REVIEW</article-title></title-group><contrib-group content-type="authors"><contrib id="741" contrib-type="author" corresp="yes"><name><given-names>MUSKAN SHRESTHA</given-names></name><xref ref-type="aff" rid="aff-1">1</xref><aff id="aff-1"><label>0</label><institution>KALINGA UNIVERSITY</institution><country>India</country></aff></contrib><contrib id="742" contrib-type="author" corresp="yes"><name><given-names>DEVESH KASHYAP</given-names></name><xref ref-type="aff" rid="aff-2">2</xref><aff id="aff-2"><label>1</label><institution>KALINGA UNIVERSITY</institution><country>India</country></aff></contrib><contrib id="743" contrib-type="author" corresp="yes"><name><given-names>Dr. Shilpi Shrivastava</given-names></name><xref ref-type="aff" rid="aff-3">3</xref><aff id="aff-3"><label>2</label><institution>KALINGA UNIVERSITY</institution><country>India</country></aff></contrib></contrib-group><contrib-group content-type="editors"><contrib contrib-type="editor"/></contrib-group><pub-date pub-type="epub" data-type="pub" iso-8601-date="2026-04-03"><day>03</day><month>04</month><year iso-8601-date="2">2026</year></pub-date><volume>3</volume><elocation-id>V3-I2-2025</elocation-id><history><date date-type="received" iso-8601-date="2026-01-27"><day>27</day><month>01</month><year iso-8601-date="2026">2026</year></date><date date-type="revised" iso-8601-date="2026-01-27"><day>27</day><month>01</month><year iso-8601-date="2026"/></date><date date-type="accepted" iso-8601-date="2026-01-27"><day>27</day><month>01</month><year iso-8601-date="2026"/></date></history><permissions><copyright-statement>&#xA9;2026 MUSKAN SHRESTHA Year Corresponding Author</copyright-statement><copyright-year>2026</copyright-year><copyright-holder>MUSKAN SHRESTHA</copyright-holder><license href="https://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (ISRDO) and either DOI or URL of the article must be cited.<ext-link ext-link-type="uri" href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link></license-p></license></permissions><self-uri href="https://isrdo.org/journal/SRJMH/currentissue/pharmacological-potential-medicinal-uses-and-bioactive-properties-of-azadirachta-indica-neem-a-systematic-review"/><abstract><p>Scientific name of neem is AZADIRACHTA INDICA. ARISHTHA is the sanskrit name of neem tree that means helper for sickness. Neem also has various medicinal property and has been used in worldwide in recent years. It is also used in ayurveda medicine, homoeopathic and Unani medicine and also become the centre of attention of in modern medicine. It also elaborates a wide variety of biologically active compound that are chemically different and structurally elaborated. In neem tree all parts like leaves, flower, fruits, seeds, root and bark are used for the treatment of skin diseases, infection, dental disorder, inflammation, etc.&nbsp;Neem leaf extract is also known as IRAB has been used against malaria, HIV- AIDS and cancer. Its element has been indicated to exhibit anti-inflammatory, anti-hyperglycaemic, antioxidant, antidiabetic immune modulatory, antiviral, antimutagenic and anticarcinogenic properties. Neem also consists of compounds like flavonoids, glycosides, tannins and aliphatic compounds. It also useful for heart illnesses, hepatitis, psoriasis, ulcers, etc. Neem are used in various research fields of food safety, virology, mycology, bacteriology, etc. The biological, pharmacological and toxicological properties of neem can be analyses by modern techniques like NMR spectroscopy, infra-red spectroscopy, HPLC-MS, etc.&nbsp;</p></abstract><kwd-group kwd-group-type="author"><kwd>AZADIRACHTA INDICA</kwd><kwd> medicinal properties</kwd><kwd> biological activity</kwd><kwd> neem</kwd><kwd> pharmacological properties</kwd></kwd-group><funding-group><funding-statement>This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</funding-statement></funding-group></article-meta></front><back><sec sec-type="data-availability"><title>Data Availability</title><p>All data generated or analyzed during this study are included in this published article.</p></sec><sec sec-type="COI-statement"><title>Conflicts of Interest</title><p>The authors declare that there is no conflict of interest regarding the publication of this article.</p></sec><sec sec-type="author-contributions"><title>Authors&#x2019; Contributions</title><p>Author A conceptualized and designed the study. Author A and Author B performed the literature search, data analysis, and manuscript drafting. Both authors critically revised the manuscript and approved the final version.</p></sec><sec sec-type="funding-statement"><title>Funding Statement</title><p>This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p></sec><ack><title>Acknowledgments</title><p>The author would like to acknowledge all researchers and authors whose work has been cited in this systematic review.</p></ack><ref-list content-type="authoryear"><ref id="1"><label>1</label><element-citation publication-type="journal"><p>1.Subapriya, R., & Nagini, S. (2005). Medicinal properties of neem leaves: a review.
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