Case Study: Uncommon Manifestation of Advanced Renal Cancer

Title

Case Study: Uncommon Manifestation of Advanced Renal Cancer

Author

1. Lois Anne Leal, Student, University of the Philippines College of Medicine, Manila, Philippines

Abstract

In this specific case inquiry, we take a look at a 55-year-old man with hypertension who presented with an unusual kind of advanced kidney cancer. The patient first complained of extreme lethargy, a marked decrease in body weight, and an ongoing cough; nevertheless, there were no traditional signs of kidney disease, such as blood in the urine or discomfort in the flanks. A CT scan confirmed lung nodules and a 4 cm renal mass, a chest X-ray showed several nodular opacities, and a blood test showed high ESR and CRP levels; the patient also had minor liver enlargement, according to the clinical examination. Biopsies of the renal mass and lung nodules verified the presence of clear-cell renal carcinoma with pulmonary metastases. Supportive therapy for the patient's anaemia and cough was administered with sunitinib, a tyrosine kinase inhibitor. Quality of life improved, renal disease remained constant, and pulmonary lesions regressed significantly at the three- and six-month follow-ups. In patients presenting with unusual symptoms of advanced kidney carcinoma, this example emphasizes the need for thorough diagnostic imaging and interdisciplinary treatment. The results for patients may be greatly improved with early diagnosis and tailored treatment.

Keywords

Conclusion

Cases like this one highlight how important it is to be vigilant when recognizing advanced kidney cancer, particularly in individuals who have unusual symptoms. To make a prompt and correct diagnosis, it is crucial to know that renal cell carcinoma (RCC) may present in ways other than the traditional triad of hematuria, flank discomfort, and an abdominal mass. The success of therapy is greatly affected by how early the disease is detected using thorough imaging and confirmed biopsies. Metastatic renal cell carcinoma (RCC) treatment with targeted medications like sunitinib has shown encouraging outcomes, including shrinkage of metastatic lesions and stabilization of the primary tumour. To tackle the complex demands of these patients, it is essential to have multidisciplinary treatment that includes radiologists, pathologists, oncologists, and supportive care experts. The patient's quality of life is preserved by comprehensive supportive care, and the cancer is effectively treated, thanks to this collaborative approach.

Author Contrubution

The author alone is responsible for the study's conception, design, data collection, analysis, interpretation, and manuscript preparation.

Funding

This study did not receive specific financial support from funding agencies in the public, commercial, or non-profit sectors.

Conflict of Interest

The authors declare no conflicts of interest related to this study.

Data Sharing Statement

Data sharing is not part of this study.

Software And Tools Use

This research did not utilize any specific software or tools.

Acknowledgements

I appreciate the assistance and expertise provided by everyone involved in this research and manuscript, and the valuable comments from peer reviewers.