Progress in On-the-Go Genetically Modified Product Identification: Transitioning from Defense Biosensing to On-Site Sequencing
1. Jitesh Bose, G.L.A. University, Student, India
2. Akash Kumar, G.L.A. University, Student, India
Transgenic
technology has ushered in a new era, revolutionising life as we know it. As
genetically modified products emerge and gain widespread adoption, the
imperative to ensure their safety and authenticity has grown exponentially.
This demand for assurance has driven the quest for faster, more precise, and
easily deployable on-site detection systems. This perspective delves into the
current landscape of technology, exploring the realm of portable immune
biosensing, innovative portable ultrafast PCR detection devices, and
cutting-edge on-site biosensors leveraging functional nucleic acids. It also
sheds light on superior field detection instruments. Notably, the landscape
briefly mentions on-site genetic sequencing for genetically modified organisms,
an exciting frontier. This comprehensive overview showcases the current state
of detection technology and provides a compass pointing towards the future of
genetically modified product detection. It is an invaluable reference for
researchers and developers navigating this dynamic domain.
genetically modified products ultra-fast PCR portable immune biosensors functional nucleic acids GMO sequencing
The Post-Stamping
Technique (PST) has played a pivotal role in G.M. product identification, much
like the PCR technique's significance in nucleic acid detection. Recent advancements
in nanomaterials research have revitalised conventional PST methods, harnessing
their unique catalytic properties and plasmonic attributes. The integration of
nanomaterials and the growing adoption of immunoassay strips have significantly
elevated on-site G.M. product testing, yielding remarkable results.
Furthermore, ultra-fast PCR technology has reinvigorated the conventional "gold standard" for transgene detection. Its rapid response times allow versatile utilisation with various signal output devices to meet diverse sensing needs. Incorporating functional molecules and nucleic acid isothermal amplification technology has notably enhanced signal amplification and output methods, enabling the integration of micro platforms, microfluidics, semiconductors, and printed devices for on-site G.M. product testing.
Moreover, the development of quick on-site sequencing techniques has dramatically improved on-site genetically modified organism detection methodology. These advancements underscore the ongoing importance and promising future of on-site G.M. product detection, driven by technological progress and enhanced efficiency.
1. None
The author confirms sole responsibility for the following: study conception and design, data collection, analysis and interpretation of results, and manuscript preparation.
The authors did not receive any specific grants from funding agencies in the public, commercial, or non-profit sectors for the research, authorship, and/or publication of this article.
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All authors declare that they have no conflicts of interest.
I thank the following individuals for their expertise and assistance in all aspects of our study and for their help in writing the manuscript. I am also grateful for the insightful comments given by anonymous peer reviewers. Everyone's generosity and expertise have improved this study in myriad ways and saved me from many errors.
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