Endovascular Thrombectomy in Large Ischemic Core Stroke: Current Insights, Challenges, and Future Perspectives
1. Rutvik Vasoya, JNMC Raipur, Postdoctoral Researcher, India
Acute ischaemic stroke therapy has been transformed by endovascular stroke thrombectomy (EST), which mechanically removes occlusive clots from main brain arteries. Patients with minor to moderate ischaemic cores have historically benefited best from EST. Still, those with large ischaemic cores (LIC) have been seen as less suitable candidates owing to the increased risk of complications and decreased probability of functional recovery. Developments in imaging and therapeutic regimens have necessitated a new assessment of EST's function in LIC patients. This study reviews the existing literature on EST and its effects in patients with large ischaemic cores discusses both the safety and effectiveness of the procedure and looks forward to future studies that might help improve therapy for this at-risk population.
Endovascular thrombectomy Large ischemic core Stroke Large vessel occlusion (LVO) Mechanical thrombectomy Neuroimaging Reperfusion therapy Symptomatic intracranial hemorrhage (sICH) Functional recovery Neuroprotective strategies
Individuals suffering from big vessel occlusion strokes may now benefit significantly from endovascular stroke thrombectomy; however, how this procedure is applied to individuals with large ischaemic cores is still a complicated and developing field of research. Mechanical thrombectomy is still effective for many patients, even if the risk of complications is increased for those with big cores. This is due to improvements in imaging, treatment regimens, and patient selection. Future studies should concentrate on enhancing post-procedure care, creating neuroprotective measures, and honing selection criteria to improve results in this challenging patient group.
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The author alone is responsible for the study's conception, design, data collection, analysis, interpretation, and manuscript preparation.
No specific grants from any funding agencies in the public, commercial, or non-profit sectors were received for this research, authorship, or publication.
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The authors declare no conflicts of interest related to this study.
I express my gratitude to those who provided expertise and assistance throughout this study and manuscript preparation. Special thanks to the anonymous peer reviewers for their valuable feedback.
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