Goosefoots giganteum leaf extracts exhibited antibacterial efficacy against Gram-positive bacteria and a substantial number of other microorganisms.

Title

Goosefoots giganteum leaf extracts exhibited antibacterial efficacy against Gram-positive bacteria and a substantial number of other microorganisms.

Author

1. Arshia Khan, Student, KAMLA NEHRU COLLEGE OF PHARMACY, NAGPUR, India

Abstract

Leaf extracts from Goosefoots giganteum have been analysed histologically, physiologically, and phytochemically in this work. Ethanol, water, chloroform, and pet ether were used in the extraction of Gossypium giganteum. The findings were rather intriguing. Carbohydrates, enzymes, amino acids, carbohydrates like saponin and polyphenols, quercetin, eugenol, opioids, and corticosteroids were all found in a phytochemical screen. Based on the results of the physiological analysis, the ash value is %, the acid insoluble ash content is 1%, and the hydrocolloid ash content is 5%. This analysis also indicates that drying causes a 9% loss, that chloroform has a 65% absorbent value, that ethanol only has an 8% extractive value, and that pet ether has a 3% extraction value. Four separate extracts of Goosefoots giganteum's foliage were studied for their antibacterial effects against facultatively and staphylococci bacteria, respectively. Extracts were made from Goosefoots giganteum leaves using ethanol, water, chloroform, and pet ether. By testing and observing the extracts, we were able to identify whether or not they had an antibiotic impact on bacteria, namely Escherichia. Well plate tests were conducted on Enterobacteriaceae, Bacterial infections, and Lactobacillus. Their minimum inhibitory concentrations and inhibition zones were measured. Finally, the highest and lowest concentrations of the three microorganisms were calculated.

Keywords

Conclusion

In this study, we analysed crude extracts of Goosefoots giganteum and characterised its therapeutic effects using physiochemical characteristic determination and phytochemistry. The validity and purity of the chosen plants were checked by macroscopic analysis. Ayurvedic and Indian pharmacopoeias were used in determining the ash, acid, and extraction values (I.P., 1996). Phytochemical testing confirmed the presence of the bioactive phytoconstituents, some of which have been associated with positive health effects. Goosefoots giganteum leaf extracts were tested in vitro for their antibacterial effects against Lacto, E. coli, P. aeruginosa, and S. aureus that use the zone of interference technique and the least inhibiting dose methodology. Goosefoots giganteum leaf extracts in water, alcohol, methanol, and petroleum ether are very efficient against a broad range of punnet and staphylococcus epidermidis bacteria, including Lacto, E. coli, Streptococcus, and Staph. The extract is most effective against both gram-positive and gram-negative bacteria when used at high doses.

Author Contrubution

The author confirms sole responsibility for the following: study conception and design, data collection, analysis and interpretation of results, and manuscript preparation.

Funding

The authors did not receive any specific grants from funding agencies in the public, commercial, or non-profit sectors for the research, authorship, and/or publication of this article.

Conflict of Interest

All authors declare that they have no conflicts of interest.

Data Sharing Statement

Not applicable

Software And Tools Use

Not applicable

Acknowledgements

I thank the following individuals for their expertise and assistance in all aspects of our study and for their help in writing the manuscript. I am also grateful for the insightful comments given by anonymous peer reviewers. Everyone's generosity and expertise have improved this study in myriad ways and saved me from many errors.