TY - M-10173 AU - Lodha, Apurva TI - Recurrent Idiopathic Urticaria: Understanding Pathophysiology, Impact on Quality of Life, Comorbidities, and Advances in Treatment T2 - Scientific Research Journal of Medical and Health Science PY - 2024 VL - 2 IS - 2 SN - 2584-1521 AB - Recurrent idiopathic urticaria (RIU), a chronic condition affecting approximately 1% of the global population, remains a significant burden, impairing patients' quality of life and leading to multiple comorbidities. Characterized by spontaneous and unpredictable hives and angioedema, RIU can persist for weeks or months, often without an identifiable cause. This paper reviews the pathophysiology of RIU, its effect on patients' physical and mental health, common comorbidities, and current treatment strategies. We also explore recent advances in treatment options and the future of personalized medicine for managing RIU, underlining the urgent need for targeted therapies and improved patient care. KW - Recurrent idiopathic urticaria KW - Chronic urticaria KW - Quality of life (QoL) KW - Autoimmune disorders KW - Mast cell activation KW - Angioedema KW - Omalizumab KW - Antihistamines KW - Immune system dysregulation DO -