TY - M-10174
AU - Vasoya, Rutvik
TI - Endovascular Thrombectomy in Large Ischemic Core Stroke: Current Insights, Challenges, and Future Perspectives
T2 - Scientific Research Journal of Medical and Health Science

PY - 2024
VL - 2
IS - 2
SN - 2584-1521

AB - Acute ischaemic stroke therapy has been transformed by endovascular stroke thrombectomy (EST), which mechanically removes occlusive clots from main brain arteries. Patients with minor to moderate ischaemic cores have historically benefited best from EST. Still, those with large ischaemic cores (LIC) have been seen as less suitable candidates owing to the increased risk of complications and decreased probability of functional recovery. Developments in imaging and therapeutic regimens have necessitated a new assessment of EST's function in LIC patients. This study reviews the existing literature on EST and its effects in patients with large ischaemic cores discusses both the safety and effectiveness of the procedure and looks forward to future studies that might help improve therapy for this at-risk population.

KW - Endovascular thrombectomy
KW -  Large ischemic core
KW -  Stroke
KW -  Large vessel occlusion (LVO)
KW -  Mechanical thrombectomy
KW -  Neuroimaging
KW -  Reperfusion therapy
KW -  Symptomatic intracranial hemorrhage (sICH)
KW -  Functional recovery
KW -  Neuroprotective strategies
DO -