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<article xlink="http://www.w3.org/1999/xlink" mml="http://www.w3.org/1998/Math/MathML" xsi="http://www.w3.org/2001/XMLSchema-instance" ali="http://www.niso.org/schemas/ali/1.0/" noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" article-type="research-article" dtd-version="1.1" lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">isrdo-SRJMH</journal-id><journal-id journal-id-type="pmc">isrdo-SRJMH</journal-id><journal-id journal-id-type="nlm-ta">isrdo-SRJMH</journal-id><journal-title-group><journal-title>Scientific Research Journal of Medical and Health Science</journal-title><abbrev-journal-title abbrev-type="publisher" pub-type="epub">SRJMH</abbrev-journal-title></journal-title-group><issn>2584-1521</issn><publisher><publisher-name>ISRDO</publisher-name><publisher-loc>Gujarat,India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">M-10263</article-id><article-id pub-id-type="doi"/><article-categories><subj-group subj-group-type="categories"><subject>Epidemiology</subject></subj-group></article-categories><title-group><article-title>Quelling HIV: Enduring Antiretroviral Potency Amidst Initial Viremia and Its Absence</article-title></title-group><contrib-group content-type="authors"><contrib id="426" contrib-type="author" corresp="yes"><name><given-names>Lulu Adam</given-names></name><xref ref-type="aff" rid="aff-1">1</xref><aff id="aff-1"><label>0</label><institution>Kilimanjaro Christian Medical University College</institution><country>Tanzania</country></aff></contrib><contrib id="427" contrib-type="author" corresp="yes"><name><given-names>Walter Tenga</given-names></name><xref ref-type="aff" rid="aff-2">2</xref><aff id="aff-2"><label>1</label><institution>Kilimanjaro Christian Medical University College</institution><country>Tanzania</country></aff></contrib></contrib-group><contrib-group content-type="editors"><contrib contrib-type="editor"/></contrib-group><pub-date pub-type="epub" data-type="pub" iso-8601-date="2025-11-16"><day>16</day><month>11</month><year iso-8601-date="2">2025</year></pub-date><volume>3</volume><elocation-id>V3-I2-2025</elocation-id><history><date date-type="received" iso-8601-date="2025-04-29"><day>29</day><month>04</month><year iso-8601-date="2025">2025</year></date><date date-type="revised" iso-8601-date="2025-06-12"><day>12</day><month>06</month><year iso-8601-date="2025"/></date><date date-type="accepted" iso-8601-date="2025-06-12"><day>12</day><month>06</month><year iso-8601-date="2025"/></date></history><permissions><copyright-statement>&#xA9;2025 Walter Tenga Year Corresponding Author</copyright-statement><copyright-year>2025</copyright-year><copyright-holder>Walter Tenga</copyright-holder><license href="https://creativecommons.org/licenses/by/4.0/"><license-p>This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (ISRDO) and either DOI or URL of the article must be cited.<ext-link ext-link-type="uri" href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link></license-p></license></permissions><self-uri href="https://isrdo.org/journal/SRJMH/currentissue/quelling-hiv-enduring-antiretroviral-potency-amidst-initial-viremia-and-its-absence"/><abstract><p>When it comes to viremia, or measurable viral levels in the bloodstream, the Human Immunodeficiency Virus (HIV) remains a major concern for world health. Despite the revolutionary impact of antiretroviral medication (ART), obstacles to adherence, viral reservoirs, and resistant virus strains continue to pose a threat to HIV treatment. Whether or not initial viremia is present, this article investigates the long-term efficacy of antiretroviral therapy. Our research delves at the inner workings of the virus, how long-acting antiretroviral therapy (ART) affects patients, and possible approaches to attaining long-term viral suppression. Examining the current literature critically reveals new information on viral reservoirs, medicines that improve adherence, and changing treatment paradigms.</p></abstract><kwd-group kwd-group-type="author"><kwd>HIV viremia</kwd><kwd> Antiretroviral therapy (ART)</kwd><kwd> Long-acting antiretroviral therapy (LA-ART)</kwd><kwd> Cabotegravir and rilpivirine</kwd><kwd> Viral reservoirs</kwd><kwd> Drug resistance</kwd></kwd-group><funding-group><funding-statement>This study did not receive specific financial support from funding agencies in the public, commercial, or non-profit sectors.</funding-statement></funding-group></article-meta></front><back><sec sec-type="data-availability"><title>Data Availability</title><p>Data sharing is not part of this study.</p></sec><sec sec-type="COI-statement"><title>Conflicts of Interest</title><p>No conflicts of interest are reported by the authors.</p></sec><sec sec-type="author-contributions"><title>Authors&#x2019; Contributions</title><p>The author takes full responsibility for the entire study process, including design, data collection, analysis, and manuscript writing.</p></sec><sec sec-type="funding-statement"><title>Funding Statement</title><p>This study did not receive specific financial support from funding agencies in the public, commercial, or non-profit sectors.</p></sec><sec sec-type="software-information"><title>software-information</title><p>This article does not include any software or tools usage information.</p></sec><ack><title>Acknowledgments</title><p>I appreciate the assistance and expertise provided by everyone involved in this research and manuscript, and the valuable comments from peer reviewers.</p></ack><ref-list content-type="authoryear"><ref id="1"><label>1</label><element-citation publication-type="journal"><p>-</p></element-citation></ref></ref-list></back></article>
