Acute ischaemic stroke therapy has been transformed by endovascular stroke thrombectomy (EST), which mechanically removes occlusive clots from main brain arteries. Patients with minor to moderate ischaemic cores have historically benefited best from EST. Still, those with large ischaemic cores (LIC) have been seen as less suitable candidates owing to the increased risk of complications and decreased probability of functional recovery. Developments in imaging and therapeutic regimens have necessitated a new assessment of EST's function in LIC patients. This study reviews the existing literature on EST and its effects in patients with large ischaemic cores discusses both the safety and effectiveness of the procedure and looks forward to future studies that might help improve therapy for this at-risk population.
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The authors declare no conflicts of interest related to this study.
The author alone is responsible for the study's conception, design, data collection, analysis, interpretation, and manuscript preparation.
No specific grants from any funding agencies in the public, commercial, or non-profit sectors were received for this research, authorship, or publication.
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I express my gratitude to those who provided expertise and assistance throughout this study and manuscript preparation. Special thanks to the anonymous peer reviewers for their valuable feedback.
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